An endonuclease specific for single-stranded DNA selectively damages the genomic DNA and induces the SOS response.
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چکیده
منابع مشابه
An endonuclease specific for single-stranded DNA selectively damages the genomic DNA and induces the SOS response.
A plasmid carrying the bacteriophage T7.3 endonuclease gene under the control of the lacUV5 promoter could be maintained in the transcriptionally active state only in recA+ strains. In recA- strains, endonuclease induction resulted in extensive degradation of the genomic DNA and cell death. In sharp contrast, the plasmid DNA remained intact in the supercoiled form. In recA+ strains, the recA pr...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1985
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)89488-1